Competition Protects Consumers, Politicians Protect Themselves :: Politics Political Essays

Rivalry Protects Consumers, Politicians Protect Themselves Baltimore Sun political author H. L. Mencken once cautioned, The entire point of pragmatic legislative issues is to keep the people frightened, and consequently rambunctious to be directed to security, by threatening it with a perpetual arrangement of ogres, every one of them fanciful. As heros lawmakers at that point report a variety of government projects to protect an appreciative electorate from some ogre. For that security, citizens are compelled to hack up billions of dollars to back government organizations like the Federal Trade Commission (FTC), Consumer Product Safety Administration (CPSC), and the Food and Drug Administration (FDA). Would could it be that at last secures the customer? It's not government but rather rivalry - numerous makers contending with one another for our dollars. What spurs a market supervisor to have deals, present new items and administrations and unremittingly scan for different approaches to satisfy us and make us faithful clients? The simple answer is that the administrator looks for more prominent benefits, yet benefits can't be basically proclaimed in light of the fact that he has no capacity to constrain us to shop at his store. He should draw us into his store satisfying us more than our next best other option - his rival down the road. The life of the director and his workers, would be a lot simpler in the event that they could get lawmakers to express level playing field laws to secure buyers against vicious rivalry. A level playing field law may command that all food merchants charge similar costs, sell similar things, and give indistinguishable client administrations. That way rivalry would be diminished. At this moment your merchant and his workers realize that on the off chance that he charges significant expenses and offers low quality support, you will take your business somewhere else. That would bring about less business, lower benefits and perhaps chapter 11. Be that as it may, if the director and his representatives could convince legislators to sanction a level playing field law, it would be an alternate story. The indistinguishable standard applies to laborers. A few people think trade guilds, Occupational Safety and Health Administration (OSHA), and the lowest pay permitted by law laws ensure the specialist. Worker's guilds, OSHA guidelines and least wages laws do ensure the occupations and pay of certain laborers yet to the detriment of other specialists' employments and salary. Worker's organizations and many work laws are minimal in excess of a conspiracy against different specialists. Association pioneers contend that their entitlement to strike is their most incredible asset in their quest for higher wages and better working conditions.

Encyclopedia of Dating Customs and Wedding †MyAssignmenthelp.com

Question: Talk about the Encyclopedia of Dating Customs and Wedding. Answer: Presentation Each individual plans a wedding that can be associated with an amazing remainder and stands apart as the most essential day in all their years. The wedding is related with customs and feelings, and subsequently individuals attempt and give out their best when they anticipate marriage (Monger, 2013). In spite of the fact that the possibility of the wedding is age-old, it is seen that numerous new thoughts have been joined into the procedure to make it stand apart from the conventional wedding rehearses. Be that as it may, the new components have been incorporated at the same time, the typical highlights stay steady and have a significant influence in the whole wedding process. The report will concentrate on the new things in the wedding alongside the conventional practices that are yet predominant. New parts of the advanced wedding The advanced wedding is recorded with a lot of new fuses that flourish to make the marriage extraordinary and amazing in its appearance. The possibility of Event the executives and occasion structure in the wedding has had an extensive effect in making the wedding present day in its methodology. New thoughts are being made into the conventional procedure, and this amalgamation makes the occasion further energizing in the cutting edge times. A portion of the components that are engaged with the new wedding are- Goal wedding-The lady of the hour and grooms nowadays seek to marry in a totally new area and away from their home area. The occasion planning group plans for a wedding that is away from the circumstance of the families and the whole procedure of the marriage happens on that specific area. The families travel to the spot alongside the visitors, and the entire game plan is made on that new area (Durinec, 2013). That brings a demeanor of newness, and going for the wedding is such a perspective, that entices the lady of the hour and man of the hour. This is a development in the wedding business as it has lead to making the occasion increasingly agreeable and fascinating for the whole list if people to attend. The visitors are included simply like the family, and consequently every individual remembered for the procedure appreciates and acquires recollections forever. Evacuation of Patriarchal ideas The whole procedure of a dad parting with his girl to man as though he claimed her and is stubbornly dying the proprietorship to her better half is an exceptionally man centric thought. The idea has been created, and nowadays the procedure is loaded with affection, and it is apparent that the young lady isn't claimed by anybody and she is her very own individual character. The lady of the hour came in under the cloak so the husband to be couldn't see the face except if it was an ideal opportunity to kiss the lady. Such suppositions have been diminished, and the settings of such ceremonies have totally changed (Alam, 2014). The lady similarly appreciates the wedding and moves and beverages to have a fabulous time upon the arrival of the wedding, and no cultural weight or judgment is forced on the lady of the hour at early occasions. Amusement consolidating Disk Jockey for playing music and making the individuals move is novel and new. The diversion remainders in the cutting edge weddings have been turned high, and the visitors are made to appreciate each snapshot of the wedding. Beforehand individuals were concerned more with the wedding being taken well however this has changed with time and diversion has transformed into a major need for the coordinators (Sari et al., 2014). Pre-wedding shoots-The new thought of making a video and photo collection of the couple reporting their marriage in a sentimental style gives the wedding a truly necessary imaginative side. Spare the date recordings are made as the couple gives out the date of their wedding through that video and it stays with them perpetually displaying their affection for one another (Napompech, 2014). Customary practices The deep rooted conventional practices that are yet applicable to the wedding function and individuals offer significance to them as much as the new fuse. The custom of wearing a white dress in the wedding is age-old, and it is yet kept up. The lady of the hour wears the white dress, and it creates the impact of a fantasy scene at the wedding as the dresses are of pixie and princess structure. The wedding band contains jewel in it, and this is a convention that is drilled for quite a while and has its importance and use even today. The jewel mirrors the valuable bond that is made during the commitment, and it likewise exhibits the sparkle the couple may have in their marital life from that point after (Francis?Tan Mialon, 2015). The lady of the hour and husband to be leave in a vehicle after the wedding is finished and it has quite recently wedded composed on it. This act of the couple leaving the spot together after the marriage is over is age-old and has been at this point kept all the while. The vehicles that are employed for the couple to leave the wedding area are as per the topic of the wedding. For the most part, as it is a well established practice, the vintage vehicles are chosen by individuals so it loans a demeanor of sovereignty to the whole wedding. End To finish up, wedding days are one of the most critical days for individuals engaged with the procedure. The conventional practices are not totally deferred off, and new components are being added to it to make it fabulous and charming. The feelings and estimations of the individuals are spared with such practices, and subsequently it ensures that the substance of a wedding never blurs. The cutting edge marriage is much about brilliance and style, and it is the conventional traditions that keep the soul of the wedding alive. It is to be respected that individuals nowadays are slanted towards the loftiness of the occasion, and keeping in mind that doing so its quintessence gets some place disappeared if the conventional practices are not coordinated with them. Reference Alam, F. (2014). Inside the Wedding: A Critical Study of Relationships in The God of Small Things and Brick Lane.BANGLADESH RESEARCH FOUNDATION, 158. Recovered from: https://www.researchfoundbd.org/pictures/Vol.3-No.2-2014.pdf#page=171 Durinec, N. (2013). Goal weddings in the Mediterranean.Hospitality and Tourism Management-2013, 1. Recovered from: https://tiikm.com/distribution/ICOHT-2013-continuing book.pdf#page=12 Francis?Tan, A., Mialon, H. M. (2015). A Diamond Is Forever And Other Fairy Tales: The Relationship Between Wedding Expenses And Marriage Duration.Economic Inquiry,53(4), 1919-1930. Recovered from: https://pdfs.semanticscholar.org/e1c8/373b9d170fa5066451b9d60f08e41091c3b3.pdf Monger, G. (2013).Marriage Customs of the World: An Encyclopedia of Dating Customs and Wedding Traditions, [2 Volumes]. Abc-clio. ISBN 1598846647, 9781598846645 Napompech, K. (2014). Characteristics In?uencing Wedding Studio Choice.Journal of Applied Sciences,14(21), 2685-2694. Recovered from: https://docsdrive.com/pdfs/ansinet/jas/0000/65343-65343.pdf Sari, D., Ozkurt, N., Hamamci, S. F., Ece, M., Yalcindag, N., Akdag, An., Akdag, Y. (2014, October). Appraisal of clamor contamination sourced from amusement puts in Antalya, Turkey. InINTER-NOISE and NOISE-CON Congress and Conference Proceedings(Vol. 249, No. 7, pp. 1072-1077). Foundation of Noise Control Engineering. Recovered from: https://www.researchgate.net/profile/Nesimi_Ozkurt/distribution/280223778_Assessment_of_noise_pollution_sourced_from_entertainment_places_in_Antalya_Turkey/joins/55adfd5008aed9b7dcdb0878/Assessment-of-clamor contamination sourced-from-diversion places-in-Antalya-Turkey.pdf

Does Minimalism Make You Complacent

Does Minimalism Make You Complacent I was explaining minimalism to a group of people at a dinner when a guy sporting a post-workday suit-and-tie combo peered at me skeptically when I told them I have no goals. Intrigue overtook his face. My life must’ve seemed so unrealistic to him since he was enmeshed in his corporate life. But that’s not his faultâ€"two years ago it seemed unrealistic to me too: in 2009 my goal-oriented life, obsessed with achievement and to-do lists, was no different from his. Then, his face still wrestling with doubt, he asked, “If you don’t have any goals, then aren’t you just being complacent?” “Yes,” I answered, “if by complacent  you mean content.” Minimalism has helped me become happier, has helped me get rid of life’s excess and be happy with what I have, has helped me live a more meaningful life: I can now focus on what’s important, and I don’t have to “achieve” to be happy. Sounds nice, doesnt it? Thats because it is. You can make the journey too: just decide it’s right for you and take action. Subscribe to The Minimalists via email.

Teaching Strategies For Learning Style Preferences

It is in this article that Beck matches three teaching strategies to learning style preferences. During which he attempts to link the 4MAT system, Dunn’s LSI, and the Renzulli Smith’s LSI to teaching strategies associated to display individual learning preferences linked to the brain’s hemispheres. The 4MAT system and Dunn’s LSI is teacher driven teaching strategies while the Renzulli Smith’s LSI allows student input into their teaching strategies. In linking the 4MAT system to teaching strategies, Beck further explores why certain teaching strategies are more successful and hemispheric appropriate when adapted to their individual natural tendencies. Student learning tendencies are associated with left- mode, right- mode, or multi- mode tendencies. Dunn s LSI includes a wide range of motivations that teachers should consider when determining individual learning styles that may include psychological and cognitive variables. However, Renzulli Smith’s LSI permits student to provide their input to list their favorite to least favorite activities. All three LSI have significance, but it is ultimately the teacher’s role to provide opportunities for each student to unharness their potential. The focus of this article was to perform research on the Preferred Teaching Approach Inventory (PTAI) including psychometric properties. This was performed to determine students preferred teaching styles impacted their personal learning styles. The research suggested thatShow MoreRelatedEducation Is Part Of Everyday Life1037 Words   |  5 Pageseducation and learn all aspect of life, learning must take place. Everyone is different and has individual styles of learning. Learning styles is defined as an individual’s mode of gaining knowledge, especially a preferred or best method (dictionary.com) Therefore, individual must have a better way of teaching others, and same goes to the person receiving the teaching. Learning is optimized by providing instructional method in means suitable for individual’s learning styles. The VARK questionnaire or knownRead MoreThe Objective Of Learning Styles966 Words   |  4 Pagesobjective of learning is to understand information intended to be learned. According to Brown (2000) learning styles is defined as the manner in which individuals perceive and process information in learning situations (Journal of Studies in Education, 2012). Depending on one s perspective, preferred learning styles help defined in multiple ways to get the most out of any learning or teaching experience. There are several ways to evaluate a person’s learning style, preference, and strategies that mayRead MoreThe Analysis : The Vark Questionnaire987 Words   |  4 PagesVARK Analyze Paper: The VARK Questionnaire According to Marcy (2001), â€Å"Learning styles† is a term used to refer to the way someone gathers, process, interprets, organizes, and thinks about information. However, each person has a different style or preference of learning, and being able to identify or understand someone’s learning styles is very important in the learning or teaching process. In the Fleming’s model, also known as VARK, an acronym stands for Visual, Auditory/aural, Read/write, andRead MoreAnalysis Paper : The Objective Of Learning1050 Words   |  5 Pagesobjective of learning is to understand information intended to be learned. According to Brown (2000) learning styles is defined as the manner in which individuals perceive and process information in learning situations (Journal of Studies in Education, 2012). Depending on one s perspective, preferred learning styles help defined in multiple ways to get the most out of any learning or teaching experience. There are several ways to evaluate a person’s learning style, preference, and strategies that mayRead MoreStudent Motivation And Academic Success1568 Words   |  7 Pagesacademic success of a student in college – motivation, learning preferences/styles, socioeconomic status, whether or not the student is a first generation college student, gender, and even race. With so many factors potentially contributing or hindering a student’s academic success in college; it is important for teachers to attempt to connect with students in the classroom. Adjusting instructional methods that focus on students’ learning preferences/styles can increase student motivation and can lead toRead MoreVark Assessment1111 Words   |  5 Pagesmaximum learning. The questionnaire consists of 16 questions which are aimed at isolating a learner’s preference to give them a better understanding of what is most effective for their retention of information being taught. According to the Vark questionnaire, there are four types of dominant learning styles; Visual, Aural, Read/Write and Kinesthetic. Additionally, Vark introduces a sub category of learning called multimodal. (Fleming, 2011) If the learner has a preference for Aural style of learningRead MoreEducational Advancement : Preferred Learning Style And Strategies1092 Words   |  5 PagesAdvancement: Preferred Learning Style and Strategies Learning transpires while an individual changes behavior, conduct, psychological processing, or emotional functioning as a consequence of introduction to new awareness, knowledge or experience. Precisely, a person’s learning style denotes the better approach, in which the learner captivates processes, understands comprehends and retains and recalls information. Learning style is also an individual s distinctive ways and method, learning a well-known onRead MoreEssay Vark Learning Styles1105 Words   |  5 PagesVARK Analysis Learning Style Scott T. Holman Grand Canyon University: NRS-429 June 17, 2014 VARK Analysis Learning Style Learning style is defined as an individual’s natural or habitual pattern of acquiring and processing information in learning situations (James, 1995). Most educational researchers and theorists generally agree that students learn in different ways (Tzu-Chien, 2009). There are many models that address learning styles including Davis A. Kolbs model based on ExperientialRead MoreEssay about Vark Learning Style Analysis1006 Words   |  5 PagesRunning head: VARK LEARNING STYLE ANALYSIS VARK Learning Style Analysis Kathleen Nash Grand Canyon University NRS-429V, Family Centered Health Promotion July 22, 2012 VARK Learning Style Analysis The VARK learning preference tool provides individuals with information that they can utilize to enhance their learning process by helping them to study more effectively and efficiently. The VARK tool consists of a questionnaire that the learner takes to identify which senses the individualRead MoreRelationship Between Learning Styles And Academic / Workplace Environment Essay1242 Words   |  5 PagesTHE RELATIONSHIP BETWEEN LEARNING STYLES AND ACADEMIC/WORKPLACE ENVIRONMENT 1. Learning styles: Learning styles refer to the different ways that people process and retain information and they serve as an indicator of the learning method that each student prefers. The learning styles theories/models that we will discuss about in this report are the Neil Fleming’s Visual-Auditory-Read/Write-Kinesthetic model and David Kolb’s Experiential Learning model. a. Visual-Auditory-Read/Write-Kinesthetic model:

Effective And Efficient Use Of Investment Tax Incentives

Executive Summary It has been observed from past experiences that there is ample room for effective and efficient use of investment tax incentives in Australia. It was found that tax incentives are does not make much impact on changing the investment climate and many times tax incentives turned out to be redundant – that is, investment would have been undertaken even without the incentives. The fiscal cost of tax incentives can be high, reducing opportunities for other required spending like on infrastructure, education and health care or any other sector. Effective and efficient use of tax incentives for small businesses requires careful tax designed. Many times government use income tax exemptions to attract investment or persuade for joint ventures to attract investments. Good infrastructure, long term effective policies, economic stability etc. are important for bringing investment. There is a need of have correct taxation policy to really have a great impact on domestic small business. Good governance of tax incentives is critical for small business growth. Transparency is necessity of time to facilitate accountability, providing opportunities for opening business or for extracting information for rent seekers and to curtail corruption. There are many stakeholders involved in the tax incentive proposal approval but the best in the ministry of finance that enforced and monitored by the tax administration. To grant tax incentives it should be based on rules rather thanShow MoreRelatedTax Reform For Small Businesses1433 Words   |  6 PagesExecutive Summary Tax reform is the crucial component in Government’s policy agenda so as to frame more employment, production, and opportunities. It is mostly initiated for the improvement of levy policy in order to implement social as well as the economic benefits. 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Critical Study of Apoptosis and “programmed cell death” Free Essays

Introduction Apoptosis in the hair follicle is programmed cell death, which occurs at a point during the cell cycle, when a sequence of programmed events causes the cells to be eliminated without the release of waste and harmful substances into the surrounding vicinity. Control of apoptosis is crucial to development of new and recycling of old cells within the body as over stimulation of apoptosis can be fatal, causing extreme tissue damage- examples of which are cancer sufferers. In this review we will discuss evidence from scientific experiments which investigate regulators of apoptosis and what really controls apoptosis in the hair follicle. We will write a custom essay sample on Critical Study of Apoptosis and â€Å"programmed cell death† or any similar topic only for you Order Now Apoptosis within the hair follicle cycle is controlled by many molecular processes and elements, of which include cytokines, tumor necrosis factor receptors, bcl-2 family gene products and ICE proteases (Soma et al., 1998). Apoptosis occurs during the catagen stage of follicle cycling which can also be known as the regression stage, and begins with initiation of receptors to their binding sites. This is specifically the binding of receptors that are rich in extracellular cysteine usually needed for binding, and intracellular compartments specific for signalling (Botchkareva et al., 2006). These receptors- also known as death receptors initiate the beginning of apoptosis, signalling via the mitochondrial membrane and setting in motion adapter molecules complementary to their apoptotic receptors (APO1/Fas receptor or tumor necrosis factor receptor- TNFR). Others include tyrosine kinase receptors- such as nerve growth factor (NGF), and p75 receptor- ‘p75NTR signalling is criticall y important for apoptosis in the regressing ORS and, therefore, for its shortening during catagen’ ( Botchkarev et al.,2000). These signals are conveyed into the cell via a cascade of enzymes known as caspases, which subsequently lead to the next stages of apoptosis. Investigations into apoptosis show that ‘physiological and pathological catagen is noticeably characterised by an up-regulation of ICE expression and an apparent inversion of the Bcl-2/Bax ratio in all epithelial follicle regions that undergo involution during catagen.’(Linder et al., 1997) This refers to intracellular and extracellular molecules located around the hair follicle, which show some control of the progression of cell death, when subjected to variation. The investigation proved that apoptosis within follicular keratinocytes in a normal state or diseased state occurred after a significant reduction in the Bcl-2/Bax ratio, which in turn caused activation of ICE proteases and eventually activation of endonucleases (Linder et al., 1997). This indicates that Bcl-2 and Bax ratios to an extent control apoptosis when down regulated, and then cause a domino effect to upregulate ICE proteases known as the caspase family, to eventually cause DNA to be cleaved into small er fragments, cell shrinkage and rounding, breakdown of the cytoskeleton and membrane blebbing. Caspases are the final inducer of apoptosis from physiological or pathological stimulation, and therefore play a major role in control of apoptosis, by remaining as an inactive form when apoptosis is not required, but becoming activated by the down regulation of the Bcl-2/Bax family of receptors, when apoptosis is required to take place. Caspases are mediators of apoptosis, and are defined and separated into two groups. The first group are the ‘instigators’ and begin the cascade, the second group are the ‘terminators’ which are activated by the instigators and cause the activation of other enzymes within the cell. The caspase family consists of caspase-8, caspase-10 and caspase-3, which act to activate the intrinsic pathway, and to link the extrinsic to the intrinsic pathway by releasing cytochrome c, a process which is primarily controlled by a family of proteins known as the Bcl-2 proteins. These are expressed in the epithelium, surrounding mesenchyme, a nd follicular papilla of the adult hair follicle throughout the cycle (Stenn et al., 1994). The release of cytochrome c ultimately forms a holoenzyme known as the apotosome, which is formed by the apoptosis initiator enzyme procaspase-9, and its adaptor molecule Apaf-1(Botchkareva et al., 2006). These apoptosomes then cleave and activate the procaspase into caspase-9, which subsequently turns on effector caspase-3. Caspase-3 is a major proteolytic enzyme, with the ability to defragment a wide range of molecules and substrates within the cell. The activation of caspase-3 then leads to the cell fragmentation and phagocytosis stages of hair follicle apoptosis. References http://www.nature.com/jid/journal/v126/n2/full/5700007a.html http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1858357/pdf/amjpathol00024-0099.pdf http://endo.endojournals.org/cgi/content/full/146/3/1214 http://www.fasebj.org/content/14/13/1931.long http://www.fasebj.org/content/15/9/1592.full.pdf http://www.applepoly.com/studies/Analysis_of_Apoptotic_Cell_Death_in_Human_Hair_Follicles.pdf How to cite Critical Study of Apoptosis and â€Å"programmed cell death†, Essay examples

Critical Study of Apoptosis and “programmed cell death” Free Essays

Introduction Apoptosis in the hair follicle is programmed cell death, which occurs at a point during the cell cycle, when a sequence of programmed events causes the cells to be eliminated without the release of waste and harmful substances into the surrounding vicinity. Control of apoptosis is crucial to development of new and recycling of old cells within the body as over stimulation of apoptosis can be fatal, causing extreme tissue damage- examples of which are cancer sufferers. In this review we will discuss evidence from scientific experiments which investigate regulators of apoptosis and what really controls apoptosis in the hair follicle. We will write a custom essay sample on Critical Study of Apoptosis and â€Å"programmed cell death† or any similar topic only for you Order Now Apoptosis within the hair follicle cycle is controlled by many molecular processes and elements, of which include cytokines, tumor necrosis factor receptors, bcl-2 family gene products and ICE proteases (Soma et al., 1998). Apoptosis occurs during the catagen stage of follicle cycling which can also be known as the regression stage, and begins with initiation of receptors to their binding sites. This is specifically the binding of receptors that are rich in extracellular cysteine usually needed for binding, and intracellular compartments specific for signalling (Botchkareva et al., 2006). These receptors- also known as death receptors initiate the beginning of apoptosis, signalling via the mitochondrial membrane and setting in motion adapter molecules complementary to their apoptotic receptors (APO1/Fas receptor or tumor necrosis factor receptor- TNFR). Others include tyrosine kinase receptors- such as nerve growth factor (NGF), and p75 receptor- ‘p75NTR signalling is criticall y important for apoptosis in the regressing ORS and, therefore, for its shortening during catagen’ ( Botchkarev et al.,2000). These signals are conveyed into the cell via a cascade of enzymes known as caspases, which subsequently lead to the next stages of apoptosis. Investigations into apoptosis show that ‘physiological and pathological catagen is noticeably characterised by an up-regulation of ICE expression and an apparent inversion of the Bcl-2/Bax ratio in all epithelial follicle regions that undergo involution during catagen.’(Linder et al., 1997) This refers to intracellular and extracellular molecules located around the hair follicle, which show some control of the progression of cell death, when subjected to variation. The investigation proved that apoptosis within follicular keratinocytes in a normal state or diseased state occurred after a significant reduction in the Bcl-2/Bax ratio, which in turn caused activation of ICE proteases and eventually activation of endonucleases (Linder et al., 1997). This indicates that Bcl-2 and Bax ratios to an extent control apoptosis when down regulated, and then cause a domino effect to upregulate ICE proteases known as the caspase family, to eventually cause DNA to be cleaved into small er fragments, cell shrinkage and rounding, breakdown of the cytoskeleton and membrane blebbing. Caspases are the final inducer of apoptosis from physiological or pathological stimulation, and therefore play a major role in control of apoptosis, by remaining as an inactive form when apoptosis is not required, but becoming activated by the down regulation of the Bcl-2/Bax family of receptors, when apoptosis is required to take place. Caspases are mediators of apoptosis, and are defined and separated into two groups. The first group are the ‘instigators’ and begin the cascade, the second group are the ‘terminators’ which are activated by the instigators and cause the activation of other enzymes within the cell. The caspase family consists of caspase-8, caspase-10 and caspase-3, which act to activate the intrinsic pathway, and to link the extrinsic to the intrinsic pathway by releasing cytochrome c, a process which is primarily controlled by a family of proteins known as the Bcl-2 proteins. These are expressed in the epithelium, surrounding mesenchyme, a nd follicular papilla of the adult hair follicle throughout the cycle (Stenn et al., 1994). The release of cytochrome c ultimately forms a holoenzyme known as the apotosome, which is formed by the apoptosis initiator enzyme procaspase-9, and its adaptor molecule Apaf-1(Botchkareva et al., 2006). These apoptosomes then cleave and activate the procaspase into caspase-9, which subsequently turns on effector caspase-3. Caspase-3 is a major proteolytic enzyme, with the ability to defragment a wide range of molecules and substrates within the cell. The activation of caspase-3 then leads to the cell fragmentation and phagocytosis stages of hair follicle apoptosis. References http://www.nature.com/jid/journal/v126/n2/full/5700007a.html http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1858357/pdf/amjpathol00024-0099.pdf http://endo.endojournals.org/cgi/content/full/146/3/1214 http://www.fasebj.org/content/14/13/1931.long http://www.fasebj.org/content/15/9/1592.full.pdf http://www.applepoly.com/studies/Analysis_of_Apoptotic_Cell_Death_in_Human_Hair_Follicles.pdf How to cite Critical Study of Apoptosis and â€Å"programmed cell death†, Essay examples